Department of Epidemiology and Prevention, IRCCS Istituto Neurologico Mediterraneo - NEUROMED, Pozzilli, (IS), Italy. Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, ISS, Rome, Italy. Epicomed Research Srl. Campobasso, Italy. Laboratory of Vascular Pathology. Istituto Dermopatico dell'Immacolata-IRCCS, FLMM, Rome, Italy. Department of Medicine and Surgery, University of Insubria, Varese, Italy. The Moli-sani study investigators are listed in the appendix.